CSIRO Publishing blank image blank image blank image blank imageBooksblank image blank image blank image blank imageJournalsblank image blank image blank image blank imageAbout Usblank image blank image blank image blank imageShopping Cartblank image blank image blank image You are here: Journals > Animal Production Science   
Animal Production Science
Journal Banner
  Food, Fibre and Pharmaceuticals from Animals
 
blank image Search
 
blank image blank image
blank image
 
  Advanced Search
   

Journal Home
About the Journal
Editorial Board
Contacts
Content
Online Early
Current Issue
Just Accepted
All Issues
Special Issues
Research Fronts
Reviews
Sample Issue
For Authors
General Information
Notes for Authors
Submit Article
Open Access
For Referees
Referee Guidelines
Review Article
For Subscribers
Subscription Prices
Customer Service
Print Publication Dates

New Feature

New Commenting Tool
Join the conversation and leave comments on all new journal articles.


blue arrow e-Alerts
blank image
Subscribe to our Email Alert or RSS feeds for the latest journal papers.

red arrow Connect with us
blank image
facebook   youtube

 

Article << Previous     |     Next >>   Contents Vol 52(11)

Factor XI mutation in normally fertile and repeat breeding Holstein cows in the Middle Anatolian region of Turkey: a financial approach

B. Akyuz A D, S. Sariozkan B and D. Bayram C

A Erciyes University, Faculty of Veterinary Medicine, Department of Genetics, Kayseri, Turkey.
B Erciyes University, Faculty of Veterinary Medicine, Department of Animal Health Economics and Management, Kayseri, Turkey.
C Erciyes University, Faculty of Veterinary Medicine, Department of Animal Science, Kayseri, Turkey.
D Corresponding author. Email: bakyuz@erciyes.edu.tr

Animal Production Science 52(11) 1042-1045 http://dx.doi.org/10.1071/AN12072
Submitted: 26 February 2012  Accepted: 4 June 2012   Published: 2 August 2012


 
PDF (176 KB) $25
 Export Citation
 Print
  
Abstract

The aim of this study was to compare the prevalence of factor XI deficiency (FXID) carriers and potential financial losses depending on ‘extended calving interval’ and ‘extra service’ in normally fertile and repeat breeder cows in Turkey. For this purpose, a total of 161 Holstein cows were genotyped for the FXI gene mutation originating from various herds located in the Middle Anatolian region of Turkey. In the study, animals were divided into two groups – normally fertile (n = 118) and repeat breeding (n = 43) cows. In each group, one FXID carrier animal was identified and the prevalence of the FXID carrier was found to be 0.85 and 2.33% in normally fertile and repeat breeder cows, respectively. In a financial analysis, it was determined that extended calving interval in a normally fertile cow caused $246 losses and $546 losses in a repeat breeder cow. Additionally, financial losses due to extra service per conception were calculated as $12 and $36 per cow in normally fertile and repeat breeder cows, respectively. In normally fertile and repeat breeder cows, the sum of losses due to extended calving interval and extra service was calculated as $258 (246 + 12) and $582 (546 + 36). This study found that a repeat breeder cow causes an extra $324 ($582 – $258) financial loss compared with a normally fertile cow. Consequently, unlike other genetic disorders like BLAD and DUMPS, which do not decrease the performance of carrier animals, the mutant FXI allele could lead to repeat breeder syndrome in FXID carrier cows and cause important financial losses in dairy farms.



References

Brush PJ, Anderson PH, Gunning RF (1987) Identification of factor XI deficiency in Holstein-Friesian cattle in Britain. The Veterinary Record 121, 14–17.
CrossRef | CAS |

Čítek J, Řehout V, Hanusová L, Vrabcová P (2008) Sporadic incidence of factor XI deficiency in Holstein cattle. Journal of the Science of Food and Agriculture 88, 2069–2072.
CrossRef |

Distl O (2005) The use of molecular genetics in eliminating of inherited anomalies in cattle. Archives Animal Breeding 48, 209–218.

Dochi O, Takahashi K, Hirai T, Hayakawa H, Tanisawa M, Yamamoto Y, Koyama H (2008) The use of embryo transfer to produce pregnancies in repeat-breeding dairy cattle. Theriogenology 69, 124–128.
CrossRef | CAS |

Gentry PA (1984) The relationship between factor XI coagulant and factor XI antigenic activity in cattle. Canadian Journal of Comparative Medicine 48, 58–62.

Gentry PA, Crane S, Lotz F (1975) Factor XI (plasma thromboplastin antecedent) deficiency in cattle. The Canadian Veterinary Journal. La Revue Veterinaire Canadienne 16, 160–163.

Ghanem ME, Nishibori M (2009) Genetic description of factor XI deficiency in Holstein semen in Western Japan. Reproduction in Domestic Animals 44, 792–796.
CrossRef | CAS |

Ghanem ME, Nishibori M, Nakao T, Nakatani K, Akita M (2005) Factor XI mutation in a Holstein cow with repeat breeding in Japan. Journal of Veterinary Medical Science 67, 713–715.
CrossRef | CAS |

Gurgul A, Rubis D, Slota E (2009) Identification of carriers of the mutation causing coagulation factor XI deficiency in Polish Holstein-Friesian cattle. Journal of Applied Genetics 50, 149–152.
CrossRef | CAS |

Kociba GD, Ratnoff OD, Loeb WF, Wall RL, Heider LE (1969) Bovine thromboplastin antecedent (factor XI) deficiency. Journal of Laboratory and Clinical Medicine 74, 37–41.

Marron BM, Robinson JL, Gentry PA, Beever JE (2004) Identification of a mutation associated with factor XI deficiency in Holstein cattle. Animal Genetics 35, 454–456.
CrossRef | CAS |

Meydan H, Yildiz MA, Özdil F, Gedik Y, Özbeyaz C (2009) Identification of factor XI deficiency in Holstein cattle in Turkey. Acta Veterinaria Scandinavica 51, 5
CrossRef |

Meydan H, Yildiz MA, Agerholm JS (2010) Screening for bovine leukocyte adhesion deficiency, deficiency of uridine monophosphate synthase, complex vertebral malformation, bovine citrullinaemia, and factor XI deficiency in Holstein cows reared in Turkey. Acta Veterinaria Scandinavica 52, 56
CrossRef |

Mukhopadhyaya PN, Jha M, Muraleedharan P, Gupta PP, Rathod RN, Mehta HH, Khoda VK (2006) Simulation of normal, carrier and affected controls for large-scale genotyping of cattle for factor XI deficiency. Genetics and Molecular Research 5, 323–332.

Ohba Y, Takasu M, Nishii N, Takeda E, Maeda S, Kunieda T, Kitagawa H (2008) Pedigree analysis of factor XI deficiency in Japanese Black cattle. Journal of Veterinary Medical Science 70, 297–299.
CrossRef | CAS |

Oner Y, Keskin A, Elmaci C (2010) Identification of BLAD, DUMPS, citrullinaemia and factor XI deficiency in Holstein cattle in Turkey. Asian Journal of Animal and Veterinary Advances 5, 60–65.
CrossRef | CAS |

Patel RK, Soni KJ, Chauhan JB, Singh KM, Rao KRSS (2007) Factor XI deficiency in Indian Bos taurus, Bos indicus, Bos taurus × Bos indicus crossbreds and Bubalus bubalis. Genetics and Molecular Research 30, 580–583.

Rodrigues CA, Teixeirab AA, Ferreirab RM, Ayresb H, Mancilhaa RF, Souzab AH, Baruselli PS (2010) Effect of fixed-time embryo transfer on reproductive efficiency in high-producing repeat-breeder Holstein cows. Animal Reproduction Science 118, 110–117.
CrossRef | CAS |

Sarıözkan S, Aral Y, Murat H, Aydın E, Sarıözkan S (2012) Süt sığırcılığı işletmelerinde fertilite bozukluklarından kaynaklanan finansal kayıpların hesaplanması. Ankara Üniversitesi Veteriner Fakültesi Dergisi 59, 55–60.

Watanabe D, Hirano T, Sugimoto Y, Ogata Y, Abe S, Ando T, Ohtsuka H, Kunieda T, Kawamura S (2006) Carrier rate of factor XI deficiency in stunted Japanese Black cattle. Journal of Veterinary Medical Science 68, 1251–1255.
CrossRef | CAS |

Windsor PA, Agerholm JS (2009) Inherited diseases of Australian Holstein-Friesian cattle. Australian Veterinary Journal 87, 193–199.
CrossRef |

Yalçın C (2000) Süt sığırcılığında infertiliteden kaynaklanan mali kayıplar. Lalahan Hayvancılık Araştırma Enstitüsü Dergisi 40, 39–47.


   
Subscriber Login
Username:
Password:  

 


    
Legal & Privacy | Contact Us | Help

CSIRO

© CSIRO 1996-2013