Reactions Catalyzed by Bacterial Cytochromes P450
Max J. Cryle, Jeanette E. Stok and James J. De Voss
Australian Journal of Chemistry
56(8) 749 - 762
Published: 18 July 2003
The cytochromes P450 are a large family of oxidative haemoproteins that are responsible for a wide variety of oxidative transformations in a variety of organisms. This review focuses upon the reactions catalyzed specifically by bacterial enzymes, which includes aliphatic hydroxylation, alkene epoxidation, aromatic hydroxylation, oxidative phenolic coupling, heteroatom oxidation and dealkylation, and multiple oxidations including C–C bond cleavage. The potential for the practical application of the oxidizing power of these enzymes is briefly discussed.
Full text doi:10.1071/CH03040
© CSIRO 2003