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Article << Previous     |     Next >>   Contents Vol 56(8)

Reactions Catalyzed by Bacterial Cytochromes P450

Max J. Cryle, Jeanette E. Stok and James J. De Voss

Australian Journal of Chemistry 56(8) 749 - 762
Published: 18 July 2003

Abstract

The cytochromes P450 are a large family of oxidative haemoproteins that are responsible for a wide variety of oxidative transformations in a variety of organisms. This review focuses upon the reactions catalyzed specifically by bacterial enzymes, which includes aliphatic hydroxylation, alkene epoxidation, aromatic hydroxylation, oxidative phenolic coupling, heteroatom oxidation and dealkylation, and multiple oxidations including C–C bond cleavage. The potential for the practical application of the oxidizing power of these enzymes is briefly discussed.



Full text doi:10.1071/CH03040

© CSIRO 2003

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