Animal Production Science Animal Production Science Society
Food, fibre and pharmaceuticals from animals
RESEARCH ARTICLE

The effect of the dietary protein restriction and re-feeding on the content of leptin, IGF-I and urea nitrogen in the blood plasma and growth performance in pigs

M. Brestenský A C , S. Nitrayová A , A. V. Sirotkin A B , P. Patráš A and J. Heger A
+ Author Affiliations
- Author Affiliations

A National Agricultural and Food Centre, Research Institute of Animal Production Nitra, Hlohovecká 2, Lužianky, 951 41, Slovakia.

B Constantine the Philosopher University in Nitra, 949 74 Nitra, Slovakia.

C Corresponding author. Email: m_brestensky@vuzv.sk

Animal Production Science - https://doi.org/10.1071/AN16333
Submitted: 19 May 2016  Accepted: 16 November 2016   Published online: 30 January 2017

Abstract

The aim of the present study was to examine the effect of the dietary protein restriction on the plasma concentrations of leptin, insulin-like growth factor (IGF-I), blood urea nitrogen (BUN) and growth performance in growing pigs. A total of 12 gilts were divided into experimental (ET) and control (CT) treatments. After the 14-day dietary restriction period during which the ET fed a low-protein diet (LPD, 5% of crude protein) and the CT fed a standard diet (SD, 16% of crude protein) the second 14-day re-feeding period followed, in which LPD was replaced by a SD that was fed by the both treatments. During the dietary protein restriction reduced (P < 0.05) N intake, average daily gain (ADG), concentration of BUN and tendency (P = 0.084) to the lower IGF-I in ET compared with CT were observed. Feed to gain ratio was greater (P < 0.05) in ET. During the subsequent re-feeding period, there was a tendency to the greater daily feed intake (P = 0.068) and N intake (P = 0.070), greater (P < 0.05) ADG, BUN and plasma leptin but no IGF-I in ET. These observations suggest that dietary protein restriction promotes body growth in pigs, which is associated with increase in blood leptin and BUN level in ET during the re-feeding, indicating that the increased ADG can be due to increased fat deposition but not of protein synthesis.

Additional keywords: blood urea nitrogen, dietary restriction, pig.


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