Antifungal Thiosulfonates: Potency with Some Selectivity

Abstract

A series of thiosulfonates have been prepared and tested against Aspergillus niger and Aspergillus flavus. In general, the thiosulfonates are moderate antifungal agents—more potent than corresponding inactive disulfides and less potent than corresponding very active fungitoxic disulfides. Apair of thiosulfonates show high selectivity, each killing only one kind of fungus.