Synthesis and Properties of a Mesylated ArgoGel Resin

Abstract

Treatment of ArgoGel-OH with methanesulfonylchloride and triethylamine gives ArgoGel-OMs to which can be coupled the salt of a hydroxycarboxylic acid (quinates 1c, 3b, or sodium salicylate) and the caesium salt of N-Boc–amino acid. The phenoxide derived from 4-hydroxybenzyl alcohol can also be coupled to this new resin to give a Wang linker.