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RESEARCH ARTICLE
Contents Vol 71(4)

Bromination of Acridine*

Graham S. Chandler A C and Wolfgang H. F. Sasse B
+ Author Affiliations
- Author Affiliations

A School of Molecular Sciences, University of Western Australia, Crawley, WA 6009, Australia.

B Deceased. Formerly of CSIRO Molecular Science, Bag 10, Clayton South, Vic. 3169, Australia.

C Corresponding author. Email: graham.chandler@uwa.edu.au

Australian Journal of Chemistry 71(4) 285-288 https://doi.org/10.1071/CH17619
Submitted: 30 November 2017  Accepted: 21 January 2018   Published: 15 February 2018

Abstract

The quantitative determination of the products of bromination of acridine in concentrated sulfuric acid and glacial acetic acid is described. In both cases, the only monobromo products were the 2- and 4-substituted compounds. With sulfuric acid, the 4-isomer predominates whereas in acetic acid, the 2-isomer is predominant. This work expands substantially on the tiny amount of previous work on halogenation of dibenzo-annelated pyridines.


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