The Chemical Constituents of Himantandra (Galbulimima) Species. IV. The Structures of Himbacine, Himbeline, Himandravine, and Himgravine

Abstract

By an extensive series of degradations involving dehydrogenation, exhaustive methylation, and oxidation, the structure of himbacine is established. It is the first member of a new group of alkaloids. By simple transformations, himbeline, himandravine, and himgravine are shown to be closely related to himbacine and their structures also established.