Benzo[c]cinnoline derivatives. II. Reactions of Benzo[c]cinnolines with lithium dialkylaniides

Abstract

2-Chlorobenzo[c]cinnoline has been found to yield 4-dimethylaminobenzo[c]-cinnoline and 2,4,7-tris(dimethylamino)benzo[c]cinnoline on reaction with lithium dimethylamide. The same products are formed (although in a different ratio) from benzo[c]cinnoline and lithium dimethylamide. 4-Dimethylaminobenzo[c]cinnoline gives the 2,4,7-tris(dimethylamino) compound in low yield with lithium dimethyl-amide; but 2-dimethylaminobenzo [c]cinnoline appears to be completely unreactive. 4-Diethylaminobenzo[c]cinnoline is formed in the interaction of benzo[c]cinnoline and lithium diethylamide.