Acridone studies. IV. The bromination of melicopicine, melicopidine, and their nor-derivatives in methanol

Abstract

Melicopicine (1,2,3,4-tetramethoxy-10-methylacridone) and melicopidine (1,4-dimethoxy-10-methyl-2,3-methylenedioxyacridone) react with bromine in methanol to yield compounds which have been formed by addition of two methoxyl groups to the substituted aromatic ring, and are isolated as salts of arylhypobromites. Normelicopicine and normelicopidine undergo similar reactions, but unlike melicopine and normelicopine which give the same product,¹ the products are different from those obtained from the methylated compounds. Some reactions of these compounds are described.