Acridone studies. V. The bromination of evoxanthine and norevoxanthine in methanol

Abstract

Evoxanthine (1-methoxy-10-methyl-2,3-methylenedioxyacridone) adds bro- mine and methanol to the 1- and 2-positions in preference to substitution at the vacant 4-position. With norevoxanthine the o- complex intermediate in the aromatic bromination has a sufficiently long lifetime to be trapped as an addition compound. Reactions to prove the structures of the compounds are described.