New alkaloids from Cryptocarya pleurosperma (Lauraceae): The structures of cryptopleuridine and cryptopleurospermine

Abstract

Two new alkaloids, cryptopleuridine and cryptopleurospermine, have been isolated from the bark of Cryptocarya pleurosperma White & Francis. From analysis of the 100-MHz n.m.r, spectra of cryptopleuridine and O-acetylcryptopleuridine, and the relationship of cryptopleuridine to cryptopleurine established from other spectroscopic data, cryptopleuridine is considered to be (5a). Spectroscopic and degradative evidence has shown that cryptopleurospermine is 2-dimethylaminoethyl-3'-hydroxy-4'-methoxy-4,5-methylenedioxybenzil (8).