Depsidone synthesis. III. Grayanic acid
P Djura and MV Sargent
Australian Journal of Chemistry
29(4) 899 - 906
Published: 1976
Abstract
The structure of the lichen depsidone grayanic acid (1) (6-heptyl-8-hydroxy-3-methoxy-1-methyl-11- oxo-11H-dibenzo[b,e][1,4]dioxepin-7-carboxylic acid) proposed by Shibata and Chiang was confirmed by the synthesis firstly of methyl O-methylgrayanate (19), and then of grayanic acid itself. The key step in both syntheses was an Ullmann reaction.https://doi.org/10.1071/CH9760899
© CSIRO 1976
