Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science
RESEARCH ARTICLE

Central nervous system active compounds. I. The synthesis of some caprolactam derivatives substituted at N1, C2 and C3

T Duong, RH Prager, AD Ward and DIB Kerr

Australian Journal of Chemistry 29(12) 2651 - 2665
Published: 1976

Abstract

The synthesis of a number of caprolactam derivatives with alkyl, aryl and hetero atom substituents at N1, C2 and C3 is described. Alkylation and arylation at C3 by a variety of methods is discussed. Some of these compounds are powerful convulsing agents; a few are depressants.

https://doi.org/10.1071/CH9762651

© CSIRO 1976


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