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Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science
RESEARCH ARTICLE

DNA Binding Compounds. V. Synthesis and Characterization of Boron Containing Bibenzimidazoles Related to the DNA Minor Groove Binder, Hoechst-33258

DP Kelly, SA Bateman, RF Martin, ME Reum, M Rose and ARD Whittaker

Australian Journal of Chemistry 47(2) 247 - 262
Published: 1994

Abstract

The synthesis and characterization of four novel boron-containing bibenzimidazoles related to the DNA minor groove binder Hoechst 33258 are reported. Such compounds, particularly their 1°B-enriched forms, have potential as agents for boron neutron capture therapy which is used in the treatment of cancers.

https://doi.org/10.1071/CH9940247

© CSIRO 1994

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