Functional Plant Biology Functional Plant Biology Society
Plant function and evolutionary biology
REVIEW

Vacuolar convolution: possible mechanisms and role of phosphatidylinositol 3,5-bisphosphate

Vadim Pérez Koldenkova A C and Noriyuki Hatsugai B
+ Author Affiliations
- Author Affiliations

A Laboratorio Nacional de Microscopía Avanzada, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Av. Cuauhtémoc, 330, Col. Doctores, Del. Cuauhtémoc. 06720, México D.F., Mexico.

B Department of Plant Biology, Microbial and Plant Genomics Institute, University of Minnesota St Paul, MN 55108, USA.

C Corresponding author. Email: vadim.perez@imss.gob.mx

Functional Plant Biology 44(8) 751-760 https://doi.org/10.1071/FP16443
Submitted: 31 December 2016  Accepted: 19 May 2017   Published: 16 June 2017

Abstract

The central or lytic vacuole is the largest intracellular organelle in plant cells, but we know unacceptably little about the mechanisms regulating its function in vivo. The underlying reasons are related to difficulties in accessing this organelle without disrupting the cellular integrity and to the dynamic morphology of the vacuole, which lacks a defined structure. Among such morphological changes, vacuolar convolution is probably the most commonly observed event, reflected in the (reversible) transformation of a large central vacuole into a structure consisting of interconnected bubbles of a smaller size. Such behaviour is observed in plant cells subjected to hyperosmotic stress but also takes place in physiological conditions (e.g. during stomatal closure). Although vacuolar convolution is a relatively common phenomenon in plants, studies aimed at elucidating its execution mechanisms are rather scarce. In the present review, we analyse the available evidence on the participation of the cellular cytoskeleton and ion transporters in vacuolar morphology dynamics, putting special emphasis on the available evidence of the role played by phosphatidylinositol 3,5-bisphosphate in this process.

Additional keywords: guard cells, hyperosmotic shock, PtdIns(3,5)P2, vacuolar fragmentation, yeast.


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