Register      Login
Journal of Primary Health Care Journal of Primary Health Care Society
Journal of The Royal New Zealand College of General Practitioners
RESEARCH ARTICLE (Open Access)

Safer Prescribing and Care for the Elderly (SPACE): feasibility of audit and feedback plus practice mail-out to patients with high-risk prescribing

Katharine Wallis 1 , Rebecca Tuckey 1
+ Author Affiliations
- Author Affiliations

1 The University of Auckland, General Practice and Primary Health Care, Auckland, New Zealand

Correspondence to: Katharine Wallis, The University of Auckland, General Practice and Primary Health Care, Private Bag 92019, Auckland 1142, New Zealand. Email: k.wallis@auckland.ac.nz

Journal of Primary Health Care 9(2) 145-152 https://doi.org/10.1071/HC17018
Published: 30 June 2017

Journal Compilation © Royal New Zealand College of General Practitioners 2017.
This is an open access article licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Abstract

INTRODUCTION: High-risk prescribing in general practice is common and places patients at increased risk of adverse events.

AIM: The Safer Prescribing and Care for the Elderly (SPACE) intervention, comprising audit and feedback plus practice mail-out to patients with high-risk prescribing, was designed to promote medicines review and support safer prescribing. This study aims to test the SPACE intervention feasibility in general practice.

METHODS: This feasibility study involved an Auckland Primary Health Organisation (PHO), a clinical advisory pharmacist, two purposively sampled urban general practices, and seven GPs. The acceptability and utility of the SPACE intervention were assessed by semi- structured interviews involving study participants, including 11 patients with high-risk prescribing. Interviews were audio-recorded, transcribed verbatim and analysed using a general inductive approach to identify emergent themes.

RESULTS: The pharmacist said the SPACE intervention facilitated communication with GPs, and provided a platform for their clinical advisory role at no extra cost to the PHO. GPs said the feedback session with the pharmacist was educational but added to time pressures. GPs selected 29 patients for the mail-out. Some GPs were concerned the mail-out might upset patients, but patients said they felt cared for. Some patients intended to take the letter to their next appointment and discuss their medicines with their GP; others said there were already many things to discuss and not enough time. Some patients were confused by the medicines information brochure.

DISCUSSION: The SPACE intervention is feasible in general practice. The medicines information brochure needs simplification. Further research is needed to test the effect of SPACE on high-risk prescribing.

KEYWORDS: Prescription medicines; patient safety; ageing; primary health care


References

[1]  Pirmohamed M, James S, Meakin S, et al. Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients. BMJ. 2004; 329 15–9.
Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients.Crossref | GoogleScholarGoogle Scholar |

[2]  Guthrie B, McCowan C, Davey P, et al. High risk prescribing in primary care patients particularly vulnerable to adverse drug events: cross sectional population database analysis in Scottish general practice. BMJ. 2011; 342 d3514
High risk prescribing in primary care patients particularly vulnerable to adverse drug events: cross sectional population database analysis in Scottish general practice.Crossref | GoogleScholarGoogle Scholar |

[3]  Meier F, Maas R, Sonst A, et al. Adverse drug events in patients admitted to an emergency department: an analysis of direct costs. Pharmacoepidemiol Drug Saf. 2015; 24 176–86.
Adverse drug events in patients admitted to an emergency department: an analysis of direct costs.Crossref | GoogleScholarGoogle Scholar |

[4]  Thomsen LA, Winterstein AG, Søndergaard B, et al. Systematic review of the incidence and characteristics of preventable adverse drug events in ambulatory care. Ann Pharmacother. 2007; 41 1411–26.
Systematic review of the incidence and characteristics of preventable adverse drug events in ambulatory care.Crossref | GoogleScholarGoogle Scholar |

[5]  Howard RL, Avery AJ, Slavenburg S, et al. Which drugs cause preventable admissions to hospital? A systematic review. Br J Clin Pharmacol. 2007; 63 136–47.
Which drugs cause preventable admissions to hospital? A systematic review.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD2s%2FntVSntA%3D%3D&md5=85706a73e71e24ba80994a67679db4c2CAS |

[6]  Ministry of Health. Pharmaceutical collection. 2016.

[7]  Fried TR, O’Leary J, Towle V, et al. Health outcomes associated with polypharmacy in community-dwelling older adults: a systematic review. J Am Geriatr Soc. 2014; 62 2261–72.
Health outcomes associated with polypharmacy in community-dwelling older adults: a systematic review.Crossref | GoogleScholarGoogle Scholar |

[8]  Guaraldo L, Cano FG, Damasceno GS, Rozenfeld S. Inappropriate medication use among the elderly: a systematic review of administrative databases. BMC Geriatr. 2011; 11 79
Inappropriate medication use among the elderly: a systematic review of administrative databases.Crossref | GoogleScholarGoogle Scholar |

[9]  Davidoff AJ, Miller GE, Sarpong EM, et al. Prevalence of potentially inappropriate medication use in older adults using the 2012 Beers criteria. J Am Geriatr Soc. 2015; 63 486–500.
Prevalence of potentially inappropriate medication use in older adults using the 2012 Beers criteria.Crossref | GoogleScholarGoogle Scholar |

[10]  Opondo D, Eslami S, Visscher S, et al. Inappropriateness of medication prescriptions to elderly patients in the primary care setting: a systematic review. PLoS One 2012; 7 e43617
Inappropriateness of medication prescriptions to elderly patients in the primary care setting: a systematic review.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC38Xht1GqsLbO&md5=c69ee207add653b74b623ddd1c36d919CAS |

[11]  Scott IA, Hilmer SN, Reeve E, et al. Reducing inappropriate polypharmacy: the process of deprescribing. JAMA Intern Med. 2015; 175 827–34.

[12]  Wallis KA, Andrews A, Henderson M. Swimming against the tide: primary care physicians’ views on deprescribing in everyday practice. Ann Fam Med. 2017; In press

[13]  Tomlin AM, Gillies TD, Tilyard MW, Dovey SM. Variation in the pharmaceutical costs of New Zealand general practices: a national database linkage study. J Public Health. 2016; 38 138–46.
Variation in the pharmaceutical costs of New Zealand general practices: a national database linkage study.Crossref | GoogleScholarGoogle Scholar |

[14]  Health Quality 8 Safety Commission New Zealand. Atlas of healthcare variation: polypharmacy in older people. New Zealand: HQ8SC; 2015. [cited 2016 May 9]. Available from: http://www.hqsc.govt.nz/our-programmes/health-quality-evaluation/projects/atlas-of-healthcare-variation/polypharmacy-in-older-people/

[15]  Patterson SM, Cadogan CA, Kerse N, et al. Interventions to improve the appropriate use of polypharmacy for older people. Cochrane Database Syst Rev 2014; 10 CD008165

[16]  Duerden M, Avery T, Payne R. Polypharmacy and medicines optimisation: making it safe and sound. London, UK: King's Fund; 2013. [cited 2014 Nov 10]. Available from: http://www.kingsfund.org.uk/sites/files/kf/field/field_publication_file/polypharmacy-and-medicines-optimisation-kingsfund-nov13.pdf

[17]  Dreischulte T, Donnan P, Grant A, et al. Safer prescribing — a trial of education, informatics, and financial incentives. N Engl J Med. 2016; 374 1053–64.
Safer prescribing — a trial of education, informatics, and financial incentives.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC28XhtlOlurvK&md5=fd38dc906d0500ec4de7f2a06dcdd56eCAS |

[18]  Roughead EE, Ellett LMK, Ramsay EN, et al. Bridging evidence-practice gaps: improving use of medicines in elderly Australian veterans. BMC Health Serv Res. 2013; 13 514
Bridging evidence-practice gaps: improving use of medicines in elderly Australian veterans.Crossref | GoogleScholarGoogle Scholar |

[19]  Avery AJ, Rodgers S, Cantrill JA, et al. A pharmacist-led information technology intervention for medication errors (PINCER): a multicentre, cluster randomised, controlled trial and cost-effectiveness analysis. Lancet. 2012; 379 1310–9.

[20]  Mugunthan K, McGuire T, Glasziou P. Minimal interventions to decrease long-term use of benzodiazepines in primary care: a systematic review and meta-analysis. Br J Gen Pract. 2011; 61 e573–78.
Minimal interventions to decrease long-term use of benzodiazepines in primary care: a systematic review and meta-analysis.Crossref | GoogleScholarGoogle Scholar |

[21]  Narayan SW, Nishtala PS. Prevalence of potentially inappropriate medicine use in older New Zealanders: a population-level study using the updated 2012 Beers criteria. J Eval Clin Pract. 2015; 21 633–41.
Prevalence of potentially inappropriate medicine use in older New Zealanders: a population-level study using the updated 2012 Beers criteria.Crossref | GoogleScholarGoogle Scholar |

[22]  Nishtala PS, Bagge ML, Campbell AJ, Tordoff JM. Potentially inappropriate medicines in a cohort of community dwelling older people in New Zealand. Geriatr Gerontol Int. 2014; 14 89–93.
Potentially inappropriate medicines in a cohort of community dwelling older people in New Zealand.Crossref | GoogleScholarGoogle Scholar |

[23]  Thomas DR. A general inductive approach for analyzing qualitative evaluation data. Am J Eval. 2006; 27 237–46.
A general inductive approach for analyzing qualitative evaluation data.Crossref | GoogleScholarGoogle Scholar |

[24]  Braun V, Clarke V. Using thematic analysis in psychology. Qual Res Psychol. 2006; 3 77–101.
Using thematic analysis in psychology.Crossref | GoogleScholarGoogle Scholar |

[25]  Clyne B, Fitzgerald C, Quinlan A, et al. Interventions to address potentially inappropriate prescribing in community-dwelling older adults: a systematic review of randomized controlled trials. J Am Geriatr Soc. 2016; 64 1210–22.
Interventions to address potentially inappropriate prescribing in community-dwelling older adults: a systematic review of randomized controlled trials.Crossref | GoogleScholarGoogle Scholar |

[26]  Guthrie B, Kavanagh K, Robertson C, et al. Data feedback and behavioural change intervention to improve primary care prescribing safety (EFIPPS): multicentre, three arm, cluster randomised controlled trial. BMJ. 2016; 354 i4079

[27]  Jamtvedt G, Young JM, Kristoffersen DT, et al. Audit and feedback: effects on professional practice and health care outcomes. Cochrane Database Syst Rev. 2006; 2 CD000259
Audit and feedback: effects on professional practice and health care outcomes.Crossref | GoogleScholarGoogle Scholar |

[28]  Ivers N, Jamtvedt G, Flottorp S, et al. Audit and feedback: effects on professional practice and healthcare outcomes. Cochrane Database Syst Rev 2012; CD000259
Audit and feedback: effects on professional practice and healthcare outcomes.Crossref | GoogleScholarGoogle Scholar |

[29]  Tannenbaum C, Martin P, Tamblyn R, et al. Reduction of inappropriate benzodiazepine prescriptions among older adults through direct patient education: the EMPOWER cluster randomized trial. JAMA Intern Med. 2014; 174 890–8.