Healthcare Infection Healthcare Infection Society
Official Journal of the Australasian College for Infection Prevention and Control
RESEARCH ARTICLE

Compliance with international guidelines on antibiotic prophylaxis for elective surgeries at a tertiary-level hospital in the Philippines

Maria Isabel P. Nabor A , Brian S. Buckley A B C and Marie Carmela M. Lapitan A
+ Author Affiliations
- Author Affiliations

A Department of Surgery, Philippine General Hospital, Manila, Philippines.

B Institute of Applied Health Sciences, University of Aberdeen, Scotland.

C Corresponding author. Email: briansbuckley@gmail.com

Healthcare Infection 20(4) 145-151 https://doi.org/10.1071/HI15018
Submitted: 25 August 2015  Accepted: 5 October 2015   Published: 28 October 2015

Abstract

Background: Surgical site infections (SSIs) are a major cause of morbidity, associated with extended hospital stays, increasing costs and even death. Perioperative antibiotic prophylaxis has been proven to prevent SSIs. Guidelines have been published to promote best practice but studies continue to highlight poor compliance.

Objective: This study aimed to assess adherence to antibiotic prophylaxis guidelines in common surgical operations in the teaching hospital of the national university in the Philippines.

Methods: This was a medical records-based, cross-sectional study. Common surgical procedures included were breast surgery, enterostomy closure, open and laparoscopic colectomy, and open and laparoscopic cholecystectomy performed from December 2013 to March 2014. Data were extracted relating to patients’ demographic characteristics, types of surgery, prophylactic antibiotic choice, route, dose, timing, redosing and duration of prophylaxis. Observed antibiotic prophylaxis was compared with guidelines.

Results: Of the 244 cases that warranted prophylaxis, 93% were given antibiotics. Of these, 44% conformed with the guideline for type of antibiotic, 39% for dose, 100% for route, 45% for timing, 93% for redosing, and 67% for duration. Only 13% conformed to guidelines for all parameters of prophylaxis. Most cholecystectomies received Cefuroxime, no longer recommended by latest international guidelines. Of the laparoscopic surgeries, 38% received antibiotics earlier than the 1 hour before surgery recommended in latest guidelines.

Conclusions: Ensuring surgeons fully follow guidelines on antibiotic prophylaxis remains a challenge, as highlighted by this study and others conducted around the world. Awareness-raising initiatives might be beneficial at institutional level to improve compliance with best practice guidelines.

Additional keywords: clinical guidelines, perioperative antibiotic prophylaxis.


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