Proton Induced X-ray Emission for Measurement of Bromine in Micro Quantities of Human Blood Plasma

Abstract

Studies have been made with proton induced X-ray emission to measure bromine in human blood plasma, and thereby estimate the extracellular fluid volume which is a determinant of biological importance. With careful attention to sample preparation, the method is precise. Since only very small amounts (less than O· 1 ml) of material are needed, the technique is applicable to the newborn and to small mammals.