Reproduction, Fertility and Development Reproduction, Fertility and Development Society
Vertebrate reproductive science and technology
RESEARCH ARTICLE

A journey through horse cloning

Andrés Gambini A B D and Marc Maserati C
+ Author Affiliations
- Author Affiliations

A Laboratory of Animal Biotechnology, Agriculture Faculty, University of Buenos Aires, Av. San Martin 4453, C1417DSE, Ciudad Autonóma de Buenos Aires, Buenos Aires, Argentina.

B National Institute of Scientific and Technological Research (CONICET), Godoy Cruz 2290, C1425FQB, Ciudad Autonóma de Buenos Aires, Buenos Aires, Argentina.

C In Vitro Clonagem Animal S/A, Rod SP 340, Km 166, (Cx Postal 238), Mogi Mirim, Sao Pablo, Brasil.

D Corresponding author. Email: gambini@agro.uba.ar

Reproduction, Fertility and Development 30(1) 8-17 https://doi.org/10.1071/RD17374
Published: 4 December 2017

Abstract

Interest in equine somatic cell nuclear transfer technology has increased significantly since the first equid clones were produced in 2003. This is demonstrated by the multiple commercial equine cloning companies having produced numerous cloned equids to date; worldwide, more than 370 cloned horses have been produced in at least six different countries. Equine cloning can be performed using several different approaches, each with different rates of success. In this review we cover the history and applications of equine cloning and summarise the major scientific advances in the development of this technology in horses. We explain the advantages and disadvantages of different procedures to produce cloned equine embryos and describe the current status of equine clone commercialisation, along with observations of differences in regional breed association registration regulations.

Additional keywords: embryo, equine, somatic cell nuclear transfer.


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