Amyloid Fibrils in Bionanotechnology
Sarah H. Waterhouse and Juliet A. Gerrard
Australian Journal of Chemistry
57(6) 519 - 523
Published: 02 June 2004
AbstractAn amyloid fibril is a highly ordered, insoluble form of protein that results when a normally soluble protein aggregates via a self-association process to form a structured nanotube. Such fibrils can now be routinely generated from purified proteins in the laboratory, and have attracted burgeoning interest due to their role in a variety of disease states. This article focusses on a new alternative direction in amyloid research, exploring the potential application of the amyloid fibril as a form of nanotubular scaffolding in bionanotechnology.
© CSIRO 2004