New Sesquiterpenes From Eremophila spectabilis

Abstract

Two new eudesmane sesquiterpenes have been isolated from Eremophila spectabilis subsp. brevis. The structures of 6β-hydroxy-7α(H)-eudesm-4-en-3-one (1) and α(H)-eudesm-4(15)-ene-3α,6β-diol (2) were elucidated by spectroscopic studies, and that of (1) was confirmed by a single-crystal room-temperature X-ray study. Crystals of (1) are monoclinic, P2₁, a 11.302(6), b 9.99(1), c 13.487(6) Ǻ, β 108.45(4), Z = 4; R was 0.052 for 2340 independent 'observed' (I > 3σ(I)) diffractometer reflections.