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Synthesis and Radiolabelling of Ipratropium and Tiotropium for Use as PET Ligands in the Study of Inhaled Drug Deposition

Fatiah Issa A , Michael Kassiou A B C , Hak-Kim Chan D and Malcolm D. McLeod A E
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A School of Chemistry, F11, University of Sydney, Sydney NSW 2006, Australia.

B Department of PET and Nuclear Medicine, Royal Prince Alfred Hospital, Camperdown NSW 2050, Australia.

C Department of Pharmacology, D06, University of Sydney, Sydney NSW 2006, Australia.

D Faculty of Pharmacy, A15, University of Sydney, Sydney NSW 2006, Australia.

E Corresponding author. Email: m.mcleod@chem.usyd.edu.au

Australian Journal of Chemistry 59(1) 53-58 https://doi.org/10.1071/CH05303
Submitted: 4 November 2005  Accepted: 30 November 2005   Published: 31 January 2006



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