
TY  - JOUR
A1  - Clark, Christopher I. 
A1  - Kelly, David P. 
A1  - Martin, Roger F. 
A1  - White, Jonathan M. 
A1  - Lobachevsky, Pavel 
T1  - Synthesis and Binding Studies of a New DNA Minor Groove Binder
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1998
VL  - 51
IS  - 3
SP  - 243
EP  - 248
KW  - 
UR  - https://doi.org/10.1071/C97115 
N2  - 2-&#91;2&#8242;-(4&#8242;&#8242;-Ethoxyphenyl)-1H-indol-6&#8242;-yl&#93;-5-(4&#8242;&#8242;&#8242;-methylpiperazin-1&#8242;&#8242;&#8242;-yl)-1H-benzimidazole (1) has been synthesized from 2-(4&#8242;-ethoxyphenyl)-1H-indole-6-carbaldehyde (4b) and 4-(4&#8242;-methylpiperazin-1&#8242;-yl)benzene-1,2-diamine (3b). The aldehyde (4b) was prepared in five steps by using a modified Leimgruber&#8211;Batcho indole synthesis. Evaluation of (1) as a DNA ligand is described. 
ER  -

