
TY  - JOUR
A1  - Kazlauskas, R 
A1  - Lidgard, RO 
A1  - Murphy, PT 
A1  - Wells, RJ 
A1  - Blount, JF 
T1  - Brominated tyrosine-derived metabolites from the sponge <I>Ianthella basta</I>
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1981
VL  - 34
IS  - 4
SP  - 765
EP  - 786
KW  - 
UR  - https://doi.org/10.1071/CH9810765 
N2  - Seven novel metabolites, each originating from four bromotyrosine units, have been isolated from the sponge Ianthella basta. Bastadin-1 (2), bastadin-2(3) and bastadin-3(4) are derived from a single phenol oxidative coupling whilst the macrocyclic compounds bastadin-4(5), bastadin-5(6), bastadin-6(8) and bastadin-7(7) are formed by two phenol oxidative coupling reactions. Compounds (2)-(8) showed potent in vitro antimicrobial activity against Gram-positive organisms. 
ER  -

