Paralytic shellfish poisons from Australian cyanobacterial blooms
Australian Journal of Marine and Freshwater Research
45(5) 761 - 771
Saxitoxin-group neurotoxins (paralytic shellfish poisons) have been identified in a cultured strain of Anabaena circinalis and in natural bloom samples in which this species was the dominant organism collected from widely distributed sites in the Murray-Darling Basin of Australia. These toxins have hitherto been isolated almost exclusively from 'red tide' dinoflagellates and contaminated shellfish. Two 'aphantoxins', which appear to be identical to two of the paralytic shellfish poisons, have been identified in a cyanobacterium from a small number of sites in New Hampshire, USA. The conclusions are supported by electrophysiological studies and by high-performance liquid chromatographic (HPLC) and fast atom bombardment-mass spectrometric (FAB-MS) analyses.
Keywords: gonyautoxin. C-toxin, sodium-channel blockers, Aphanizomenon flos-aquae, PSP
© CSIRO 1994