This study investigates smoke incursion into urban areas by examining a prescribed burn in central Georgia, USA, on 28 February 2007. Simulations were conducted with a regional modeling framework to understand transport, dispersion, and structure of smoke plumes, the air quality effects, sensitivity to emissions, and the roles of burn management strategy in mitigating the effects. The results indicate that smoke plumes first went west, but turned north-west at noon owing to a shift in wind direction. The smoke then invaded metropolitan Atlanta during the evening rush hour. The plumes caused severe air quality problems in Atlanta. Some hourly ground PM_2.5 (particulate matter not greater than 2.5 μm in diameter) concentrations at three metropolitan Atlanta locations were three to four times as high as the daily (24-h) US National Ambient Air Quality Standard. The simulated shift in the smoke transport direction and the resultant effects on air quality are supported by the satellite and ambient air measurements. Two sensitivity simulations indicate a nearly linear relation between the emission intensities and PM_2.5 concentrations. Two other simulations indicate that the impacts on air quality for the residents of Atlanta during the evening commute could have been reduced if the starting time of the burn had been altered.