Abstract

The toxicity of cholecalciferol in the rabbit was evaluated as part of an assessment of alternative toxins to sodium monofluoroacetate (1080) and pindone for large-scale rabbit control in the South Island of New Zealand. After a dose-ranging study spanning the known LD50 values for other mammals (up to 400 mg kg-1) an acute toxicity study established an LD50 of 9mg kg-1 and LD95 of 18mg kg-1 for the rabbit, which proved very susceptible to cholecalciferol.