CSIRO PUBLISHING - Australian Journal of Chemistry

Direct Synthesis of Deep Cavity p-Phenylcalix[4]arene in Poly(Ethylene Glycol), and its Self-Association in the Solid State

Mohamed Makha ^A ^B, Colin L. Raston ^A ^B and Alexandre N. Sobolev ^A

^A School of Biomedical, Biomolecular and Chemical Sciences, M310, University of Western Australia, Perth WA 6009, Australia.
^B Corresponding authors. Email: mmakha@chem.uwa.edu.au; clralston@chem.uwa.edu.au

Abstract

p-Phenylcalix[4]arene is formed directly from p-phenylphenol in 66% yield (50% isolated yield) using poly(ethylene glycol) as the reaction medium, with crystallization of the pure cavitand from toluene mediated by p-carborane. The solid-state structure comprises interlocking columnar arrays.

Australian Journal of Chemistry 59(4) 260–262 doi:10.1071/CH06080
Submitted: 8 March 2006 Accepted: 23 March 2006 Published: 1 May 2006