Anhydrous Magnesium Sulfate Mediated Solvent-Free Synthesis of Dihydropyrimidin-2(1H)-ones at Ambient Temperature

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doi:10.1071/CH07097

Anhydrous Magnesium Sulfate Mediated Solvent-Free Synthesis of Dihydropyrimidin-2(1H)-ones at Ambient Temperature

D. M. Pore ^A ^C, U. V. Desai ^A ^C, T. S. Thopate ^A, P. P. Wadgaonkar ^B

^A Department of Chemistry, Shivaji University, Kolhapur 416 004, India.
^B Polymer Science and Engineering Division, National Chemical Laboratory, Pune 411008, India.
^C Corresponding authors. Email: p_dattaprasad@rediffmail.com; uprabhu_desai@rediffmail.com





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Australian Journal of Chemistry 60(6) 435–438 http://dx.doi.org/10.1071/CH07097
Submitted: 6 April 2007 Accepted: 30 April 2007 Published online: 18 June 2007

Abstract

An anhydrous magnesium sulfate mediated solvent-free protocol is described for the synthesis of dihydropyrimidinones (Biginelli compounds) at ambient temperature.