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Article << Previous     |     Next >>   Contents Vol 45(8)

Integrated and comparative maps in livestock genomics

F. W. Nicholas

Reprogen and CRC for Innovative Dairy Products, Faculty of Veterinary Science, University of Sydney, NSW 2006, Australia. Email: frankn@vetsci.usyd.edu.au
 
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Abstract

The creation of a single integrated map incorporating all available mapping information for an unsequenced species provides the best possible resource for meta analyses of quantitative trait loci, for a backbone on which to assemble sequence and for comparative mapping. Using a strategy encapsulated in the Location DataBase, integrated maps for cattle, sheep and pigs have been produced from all publicly-available mapping information for these livestock species. A very useful tool for comparative mapping is the Oxford grid. Of particular interest are grids comparing an integrated map from an unsequenced species with the annotated sequence map from a sequenced species. By an additional iteration of the Location DataBase approach or a variant of the Oxford-grid software, it is possible to create a virtual genome of the unsequenced species, which is a map comprising predicted locations for all loci identified in the sequenced species.

Keywords: comparative map, integrated map.


   
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