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Synthesis and Characterization of a Novel Biodegradable Amphiphilic Dendritic Polyether-ester
Jin peng
Xiao A,
Hong
Wang A,
Qiang
Yi A,
Gejun
Ma A and
Xue fei
Zhang A B C
A
College of Chemistry, Xiangtan University, Xiangtan, 411105, Hunan Province, China.
B
Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Xiangtan, 411105, China.
C
Corresponding author. Email: zxf7515@yahoo.com.cn
Australian Journal of Chemistry
65(5)
545-551 http://dx.doi.org/10.1071/CH12013
Submitted: 14 January 2012 Accepted: 17 February 2012 Published:
14
May
2012
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Abstract
A novel biodegradable amphiphilic dendritic polyether-ester composed of glycerol, glycolic acid oligomer and methoxy poly(ethylene glycol) is described. The monomer unit composed of glycerol and glycolic acid was protected by tert-butyl and benzyl groups. The amphiphilic dendritic polyether-ester was prepared in high yield using sequential deprotection reactions and esterification. The structure of all compounds was confirmed by 1H NMR spectra, 13C NMR spectra, GC-MS or matrix-assisted laser desorption–ionization time-of-flight mass spectrometry, and the amphiphilic dendritic macromolecule molecular weight and distribution were measured by gel permeation chromatography. 
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