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Australian Journal of Chemistry Australian Journal of Chemistry Society
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Heck Reactions in Aqueous Miniemulsions

Hazit A. Zayas A , David Valade A , Zhongfan Jia A and Michael J. Monteiro A B
+ Author Affiliations
- Author Affiliations

A Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Brisbane, Qld 4072, Australia.

B Corresponding author. Email: m.monteiro@uq.edu.au

Australian Journal of Chemistry 65(8) 1090-1094 https://doi.org/10.1071/CH12164
Submitted: 22 March 2012  Accepted: 24 April 2012   Published: 30 May 2012

Abstract

Carrying out organic reactions in water-based nanoreactors represents a ‘green’ method for the preparation of organic compounds. This process eliminates the need for solvents, thus reducing the effect of high volumes of solvent on the environment. In this work, we demonstrate a successful Heck cross-coupling reaction, one of the most used approaches to form C–C bonds using a palladium catalyst, in a miniemulsion. The miniemulsion droplet sizes were small (25 to 42 nm), and the reactions resulted in high conversions of three different products with high trans stereoisomers.


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