Pyrimidine reactions. XXVII. Syntheses, reactivities and mass spectra of some 2-isopropylpyrimidine derivatives
DJ Brown and P .Waring
Australian Journal of Chemistry
31(6) 1391 - 1395
Syntheses of 2-(1'-bromo-1'-methylethyl)-4-chloropyrimidine (1c) and its 4-fluoro analogue (1f) are described. Rates for solvolysis of these and similar bromo compounds in 50% aqueous methanol at pH 7.0 are recorded at several temperatures. These data and some unusual facets of the mass spectra shown by 2-isopropylpyrimidines, and their α-bromo or α-methoxy derivatives, are discussed.
Full text doi:10.1071/CH9781391
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