References
Aflatoonian, B., Ruban, L., Jones, M., Aflatoonian, R., Fazeli, A., and Moore, H. (2009
).
In vitro post-meiotic germ cell development from human embryonic stem cells.
Hum. Reprod. 24, 3150–3159.
|
CrossRef |
CAS |
PubMed |
Behr, B. (1999
).
Blastocyst culture and transfer.
Hum. Reprod. 14, 5–6.
|
CrossRef |
CAS |
PubMed |
Bucay, N., Yebra, M., Cirulli, V., Afrikanova, I., Kaido, T., Hayek, A., and Montgomery, A. (2009
).
A novel approach for the derivation of putative primordial germ cells and sertoli cells from human embryonic stem cells.
Stem Cells 27, 68–77.
|
CrossRef |
CAS |
PubMed |
Cedars, M. (2005). ‘Infertility.’ (McGraw-Hill: New York.)
Chavez, S., Meneses, J., Nguyen, H., Kim, S., and Reijo Pera, R. A. (2008
).
Characterization of six new human embryonic stem cell lines (HSF-7, -8, -9, -10, -12 and -13) derived in minimal animal-component conditions.
Stem Cells Dev. 17, 535–546.
|
CrossRef |
CAS |
PubMed |
Chen, H.-F., Kuo, H.-C., Chien, C.-L., Shun, C.-T., Yao, Y.-L., Ip, P.-L., Chuang, C.-Y., Wang, C.-C., Yang, Y.-S., and Ho, H.-N. (2007
).
Derivation, characterization and differentiation of human embryonic stem cells: comparing serum-containing versus serum-free media and evidence of germ cell differentiation.
Hum. Reprod. 22, 567–577.
|
CrossRef |
PubMed |
Chuva-de-Sousa-Lopes, S., and Roelen, B. (2010
).
Review: mini-series on germ cell development on the formation of germ cells: the good, the bad and the ugly.
Differentiation 79, 131–140.
|
PubMed |
Clark, A. T., Bodnar, M. S., Fox, M. S., Rodriquez, R. T., Abeyta, M. J., Firpo, M. T., and Reijo Pera, R. A. (2004
).
Spontaneous differentiation of germ cells from human embryonic stem cells
in vitro.
Hum. Mol. Genet. 13, 727–739.
|
CrossRef |
CAS |
PubMed |
Flörke-Gerloff, S., Töpfer-Petersen, E., Müller-Esterl, W., Schill, W., and Engel, W. (1983
).
Acrosin and the acrosome in human spermatogenesis.
Hum. Genet. 65, 61–67.
|
CrossRef |
PubMed |
Fox, M. S., Clark, A. T., El Majdoubi, M., Vigne, J. L., Urano, J., Hostetler, C. E., Griswold, M. D., Weiner, R. I., and Reijo Pera, R. A. (2007
).
Intermolecular interactions of homologs of germ plasm components in mammalian germ cells.
Dev. Biol. 301, 417–431.
|
CrossRef |
CAS |
PubMed |
Gardner, D. K., Schoolcraft, W. B., Wagley, L., Schlenker, T., Stevens, J., and Hesla, J. (1998
).
A prospective randomized trial of blastocyst culture and transfer in
in-vitro fertilization.
Hum. Reprod. 13, 3434–3440.
|
CrossRef |
CAS |
PubMed |
Geijsen, N., Horoschak, M., Kim, K., Gribnau, J., Eggan, K., and Daley, G. Q. (2004
).
Derivation of embryonic germ cells and male gametes from embryonic stem cells.
Nature 427, 148–154.
|
CrossRef |
CAS |
PubMed |
Han, J., Yuan, P., Yang, H., Zhang, J., Soh, B., Li, P., Lim, S., Cao, S., Tay, J., Orlov, Y., Lufkin, T., Ng, H., Tam, W., and Lim, B. (2010
).
Tbx3 improves the germ-line competency of induced pluripotent stem cells.
Nature 463, 1096–1100.
|
CrossRef |
CAS |
PubMed |
Handyside, A., Lesko, J., Tarin, J., Winston, R., and Hughes, M. (1992
).
Birth of a normal girl after
in vitro fertilization and preimplantation diagnostic testing for cystic fibrosis.
N. Engl. J. Med. 327, 905–909.
|
CrossRef |
CAS |
PubMed |
Haston, K., Tung, J., and Reijo Pera, R. A. (2009
).
Dazl functions in maintenance of pluripotency and genetic and epigenetic programs of differentiation in mouse primordial germ cells
in vivo and
in vitro.
PLoS One 4, e5654.
|
CrossRef |
PubMed |
Hayashi, K., Ohta, H., Kurimoto, K., Aramaki, S., and Saitou, M. (2011
).
Reconstitution of the mouse germ cell specification pathway in culture by pluripotent stem cells.
Cell 146, 519–532.
|
CrossRef |
CAS |
PubMed |
Hendry, A. P., Wenburg, J. K., Bentzen, P., Volk, E. C., and Quinn, T. P. (2000
).
Rapid evolution of reproductive isolation in the wild: evidence from introduced salmon.
Science 290, 516–518.
|
CrossRef |
CAS |
PubMed |
Hubner, K., Fuhrmann, G., Christenson, L., Kehler, J., Reinbold, R., De La Fuente, R., Wood, J., Strauss, J., Boiani, M., and Scholer, H. (2003
).
Derivation of oocytes from mouse embryonic stem cells.
Science 300, 1251–1256.
|
CrossRef |
PubMed |
Hunt, P. A., and Hassold, T. J. (2002
).
Sex matters in meiosis.
Science 296, 2181–2183.
|
CrossRef |
CAS |
PubMed |
International Human Genome Sequencing Consortium (2001
).
Initial sequencing and analysis of the human genome.
Nature 409, 860–921.
|
CrossRef |
PubMed |
International Stem Cell Consortium (2007
).
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.
Nat. Biotechnol. 25, 803–816.
|
CrossRef |
PubMed |
Jaruzelska, J., Kotecki, M., Kusz, K., Spik, A., Firpo, M., and Reijo, R. A. (2003
).
Conservation of a Pumilio-Nanos complex from
Drosophila germ plasm to human germ cells.
Dev. Genes Evol. 213, 120–126.
|
CAS |
PubMed |
Kee, K., Gonsalves, J., Clark, A., and Reijo Pera, R. A. (2006
).
Bone morphogenetic proteins induce germ cell differentiation from human embryonic stem cells.
Stem Cells Dev. 15, 831–837.
|
CrossRef |
CAS |
PubMed |
Kee, K., Angeles, V., Flores, M., Nguyen, H., and Reijo Pera, R. A. (2009
).
Human
DAZL, DAZ and
BOULE genes modulate primordial germ cell and haploid gamete formation.
Nature 462, 222–225.
|
CrossRef |
CAS |
PubMed |
Kerr, C. L., and Cheng, L. (2010
).
The Dazzle in germ cell differentiation.
J. Mol. Cell. Biol. 2, 26–29.
|
CrossRef |
CAS |
PubMed |
Ma, K., Sharkey, A., Kirsch, S., Vogt, P., Keil, R., Hargreave, T. B., McBeath, S., and Chandley, A. C. (1992
).
Towards the molecular localisation of the AZF locus: mapping of microdeletions in azoospermic men within 14 subintervals of interval 6 of the human Y chromosome.
Hum. Mol. Genet. 1, 29–33.
|
CrossRef |
CAS |
PubMed |
Marques-Mari, A., Lacham-Kaplan, O., Medrano, J., Pellicer, A., and Simon, C. (2009
).
Differentiation of germ cells and gametes from stem cells.
Hum. Reprod. Update 15, 379–390.
|
CrossRef |
CAS |
PubMed |
Matzuk, M., and Lamb, D. (2002
).
Genetic dissection of mammalian fertility pathways.
Nat. Cell Biol. 4S, 41–49.
Medrano, J. V., Ramathal, C., Nguyen, H. N., Simon, C., and Reijo-Pera, R. A. (2012
).
Divergent RNA-binding proteins, dazl and vasa, induce meiotic progression in human germ cells derived
in vitro.
Stem Cells 30, 441–451.
|
CrossRef |
CAS |
PubMed |
Moore, F. L., Jaruzelska, J., Fox, M. S., Urano, J., Firpo, M. T., Turek, P. J., Dorfman, D. M., and Reijo Pera, R. A. (2003
).
Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-Like proteins.
Proc. Natl Acad. Sci. USA 100, 538–543.
|
CrossRef |
CAS |
PubMed |
Moore, F. L., Jaruzelska, J., Dorfmann, D., and Reijo Pera, R. A. (2004
).
Identification of a novel gene,
DZIP (DAZ Interacting Protein), that encodes a protein that interacts with DAZ and DAZL (Deleted in AZoospermia and DAZ-Like) and is expressed in embryonic stem cells and germ cells.
Genomics 83, 834–843.
|
CrossRef |
CAS |
PubMed |
Nicholas, C., Haston, K., Grewall, A., Longacre, T., and Reijo Pera, R. A. (2009
).
Transplantation directs oocyte maturation from embryonic stem cells and provides a therapeutic strategy for female infertility.
Hum. Mol. Genet. 18, 4376–4389.
|
CrossRef |
CAS |
PubMed |
Nicholas, C., Haston, K., and Reijo Pera, R. A. (2010
).
Intact fetal ovarian cord formation promotes mouse oocyte survival and development.
BMC Dev. Biol. 10, 2.
|
CrossRef |
PubMed |
Oakley, L., Doyle, P., and Maconochie, N. (2008
).
Lifetime prevalence of infertility and infertility treatment in the UK: results from a population-based survey of reproduction.
Hum. Reprod. 23, 447–450.
|
CrossRef |
CAS |
PubMed |
Palermo, G., Joris, H., Devroey, P., and Steirteghem, A. C. V. (1992
).
Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte.
Lancet 340, 17–18.
|
CrossRef |
CAS |
PubMed |
Panula, S., Medrano, J., Kee, K., Bergstrom, R., Nguyen, H., Byers, B., Wilson, K., Wu, J., Simon, C., Hovatta, O., and Reijo Pera, R. A. (2011
).
Human germ cell differentiation from fetal- and adult-derived induced pluripotent stem cells.
Hum. Mol. Genet. 20, 752–762.
|
CrossRef |
CAS |
PubMed |
Park, I., Zhao, R., West, J., Yabuuchi, A., Huo, H., Ince, T., Lerou, P., Lensch, M., and Daley, G. (2008
).
Reprogramming of human somatic cells to pluripotency with defined factors.
Nature 451, 141–146.
|
CrossRef |
CAS |
PubMed |
Park, T., Galic, Z., Conway, A., Lindgren, A., Handel, B. v., Magnusson, M., Richter, L., Teitell, M., Mikkola, H., Lowry, W., Plath, K., and Clark, A. (2009
).
Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells.
Stem Cells 27, 783–795.
|
CrossRef |
CAS |
PubMed |
Reijo, R., Lee, T. Y., Salo, P., Alagappan, R., Brown, L. G., Rosenberg, M., Rozen, S., Jaffe, T., Straus, D., Hovatta, O., de la Chapelle, A., Silber, S., and Page, D. C. (1995
).
Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene.
Nat. Genet. 10, 383–393.
|
CrossRef |
CAS |
PubMed |
Reijo, R., Alagappan, R. K., Patrizio, P., and Page, D. C. (1996
).
Severe oligospermia resulting from deletions of the
Azoospermia Factor gene on the Y chromosome.
Lancet 347, 1290–1293.
|
CrossRef |
CAS |
PubMed |
Reijo Pera, R. A., DeJonge, C., Bossert, N., Yao, M., Yang, J. Y. H., Asadi, N. B., Wong, W., Wong, C., and Firpo, M. T. (2009
).
Gene expression profiles of human inner cell mass cells and embryonic stem cells.
Differentiation 78, 18–23.
|
CrossRef |
PubMed |
Sabour, D., Arauzo-Bravo, M., Hubner, K., Ko, K., Greber, B., Gentile, L., Stehling, M., and Scholer, H. (2011
).
Identification of genes specific to mouse primordial germ cells through dynamic global gene expression.
Hum. Mol. Genet. 20, 115–125.
|
CrossRef |
CAS |
PubMed |
Salvador, L. M., Silva, C. P., Kostetskii, I., Radice, G. L., and Strauss, J. F. (2008
).
The promoter of the oocyte-specific gene,
Gdf9, is active in population of cultured mouse embryonic stem cells with an oocyte-like phenotype.
Methods 45, 172–181.
|
CrossRef |
CAS |
PubMed |
Saxena, R., Brown, L. G., Hawkins, T., Alagappan, R. K., Skaletsky, H., Reeve, M. P., Reijo, R., Rozen, S., Dinulos, M. B., Disteche, C. M., and Page, D. C. (1996
).
The
DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned.
Nat. Genet. 14, 292–299.
|
CrossRef |
CAS |
PubMed |
Skaletsky, H., Kuroda-Kawaguchi, T., Minx, P. J., Cordum, H. S., Hillier, L., Brown, L. G., Repping, S., Pyntikova, T., Ali, J., Bieri, T., Chinwalla, A., Delehaunty, A., Delehaunty, K., Du, H., Fewell, G., Fulton, L., Fulton, R., Graves, T., Hou, S. F., Latrielle, P., Leonard, S., Mardis, E., Maupin, R., McPherson, J., Miner, T., Nash, W., Nguyen, C., Ozersky, P., Pepin, K., Rock, S., Rohlfing, T., Scott, K., Schultz, B., Strong, C., Tin-Wollam, A., Yang, S. P., Waterston, R. H., Wilson, R. K., Rozen, S., and Page, D. C. (2003
).
The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes.
Nature 423, 825–837.
|
CrossRef |
CAS |
PubMed |
Sommer, C., Sommer, A., Longmire, T., Christodoulou, C., Thomas, D., Gostissa, M., Alt, F., Murphy, G., Kotton, D., and Mostoslavsky, G. (2010
).
Excision of reprogramming transgenes improves the differentiation potential of iPS cells generated with a single excisable vector.
Stem Cells 28, 64–74.
|
CAS |
PubMed |
Stephen, E., and Chandra, A. (1998
).
Updated projections of infertility in the United States: 1995–2025.
Fertil. Steril. 70, 30–34.
|
CrossRef |
CAS |
PubMed |
Steptoe, P. C., and Edwards, R. G. (1978
).
Birth after the reimplantation of a human embryo.
Lancet 312, 366.
|
CrossRef |
Swanson, W. J., and Vacquier, V. D. (2002
).
The rapid evolution of reproductive proteins.
Nat. Rev. Genet. 3, 137–144.
|
CrossRef |
CAS |
PubMed |
Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., and Yamanaka, S. (2007
).
Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
Cell 131, 861–872.
|
CrossRef |
CAS |
PubMed |
Teramura, T., Takehara, T., Kawata, N., Fujinami, N., Mitani, T., Takenoshita, M., Matsumoto, K., Saeki, K., Iritani, A., Sagawa, N., and Hoso, Y. (2007
).
Primate embryonic stem cells proceed to early gametogenesis
in vitro.
Cloning Stem Cells 9, 144–156.
|
CrossRef |
CAS |
PubMed |
Thomson, J. A., Itskovitz-Eldor, J., Shapiro, S. S., Waknitz, M. A., Swiergiel, J. J., Marshall, V. S., and Jones, J. M. (1998
).
Embryonic stem cell lines derived from human blastocysts.
Science 282, 1145–1147.
|
CrossRef |
CAS |
PubMed |
Tilgner, K., Atkinson, S., Yung, S., Golebiewska, A., Stojkovic, M., Moreno, R., Lako, M., and Armstrong, L. (2010
).
Expression of GFP under the control of the RNA helicase VASA permits fluorescence-activated cell sorting isolation of human primordial germ cells.
Stem Cells 28, 84–92.
|
CAS |
PubMed |
Vogt, P., Chandley, A. C., Hargreave, T. B., Keil, R., Ma, K., and Sharkey, A. (1992
).
Microdeletions in interval 6 of the Y chromosome of males with idiopathic sterility point to disruption of AZF, a human spermatogenesis gene.
Hum. Genet. 89, 491–496.
|
CrossRef |
CAS |
PubMed |
Vogt, P. H., Edelmann, A., Kirsch, S., Henegariu, O., Hirschmann, P., Kiesewetter, F., Kohn, F. M., Schill, W. B., Farah, S., Ramos, C., Hartmann, M., Hartschuh, W., Meschede, D., Behre, H. M., Castel, A., Nieschlag, E., Weidner, W., Grone, H.-J., Jung, A., Engel, W., and Haidl, G. (1996
).
Human Y chromosome azoospermia factors (AZF) mapped to different subregions in Yq11.
Hum. Mol. Genet. 5, 933–943.
|
CrossRef |
CAS |
PubMed |
Warren, L., Manos, P., Ahfeldt, T., Loh, Y., Li, H., Lau, F., Ebina, W., Mandal, P., Smith, Z., Meissner, A., Daley, G., Brack, A., Collins, J., Cowan, C., Schlaeger, T., and Rossi, D. (2010
).
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.
Cell Stem Cell 7, 618–630.
|
CrossRef |
CAS |
PubMed |
West, F., Roche-Rios, M., Abraham, S., Rao, R., Natrajan, M., Bacanamwo, M., and Stice, S. (2010
).
KIT ligand and bone morphogenetic protein signaling enhances human embryonic stem cell to germ-like cell differentiation.
Hum. Reprod. 25, 168–178.
|
CrossRef |
CAS |
PubMed |
West, F., Mumaw, J., Gallegos-Cardenas, A., Young, A., and Stice, S. (2011
).
Human haploid cells differentiated from meiotic competent clonal germ cell lines that originated from embryonic stem cells.
Stem Cells Dev. 20, 1079–1088.
|
CrossRef |
CAS |
PubMed |
Yamauchi, K., Hasegawa, K., Chuma, S., Nakatsuji, N., and Suemori, H. (2009
).
In vitro germ cell differentiation from cynomolgus monkey embryonic stem cells.
PLoS One 4, e5338.
|
CrossRef |
PubMed |
Yoshimizu, T., Obinata, M.,, and Matsui, Y. (2001
).
Stage-specific tissue and cell interactions play key roles in mouse germ cell specification.
Development 128, 481–490.
|
CAS |
PubMed |
Young, J., Dias, V., and Loveland, K. (2010
).
Defining the window of germline genesis
in vitro from murine embryonic stem cells.
Biol. Reprod. 82, 390–401.
|
CrossRef |
CAS |
PubMed |
Yu, J., Vodyanik, M., Smuga-Otto, K., Antosiewicz-Bourget, J., France, J., Tian, S., Nie, J., Jonsdottir, G., Ruotti, V., Stewart, R., Slukvin, I., and Thomson, J. (2007
).
Induced pluripotent stem cell lines derived from human somatic cells.
Science 318, 1917–1920.
|
CrossRef |
CAS |
PubMed |
Zhou, G.-B., Meng, Q.-G., and Li, N. (2010
).
In vitro derivation of germ cells from embryonic stem cells in mammals.
Mol. Reprod. Dev. 77, 586–594.
|
CrossRef |
CAS |
PubMed |
Zinn, A. R., Page, D. C., and Fisher, E. M. C. (1993
).
Turner syndrome: the case of the missing sex chromosome.
Trends Genet. 9, 90–93.
|
CrossRef |
CAS |
PubMed |