
TY  - JOUR
A1  - Nichols, Jennifer 
A1  - Smith, Austin 
A1  - Buehr, Mia 
T1  - Rat and mouse epiblasts differ in their capacity to generate extraembryonic endoderm
JF  - Reproduction, Fertility and Development
JO  - Reprod. Fertil. Dev.
Y1  - 1999
VL  - 10
IS  - 8
SP  - 517
EP  - 526
KW  - egg cylinder, embryonic stem (ES) cells, parietal endoderm.
UR  - https://doi.org/10.1071/RD98075 
N2  - In this study we have compared the in vitro differentiation potential of epiblast tissue from mouse and rat embryos. Epiblasts were isolated from egg cylinder stage embryos by microdissection and placed in culture. Rat cultures were distinguished by the copious production of parietal endoderm cells. Mouse epiblasts, in contrast, did not produce parietal endoderm. This difference in capacity to regenerate extraembryonic endoderm marks a surprising distinction in development of the pluripotential lineage between these two closely related rodents. 
ER  -

