
%0 Journal Article
%A Bend, JR 
%A Holder, GM 
%A Protos, Eva 
%A Ryan, AJ 
%T The Metabolism of Carbaryl in the Cattle Tick Boophilus Mioroplus (Canestrini)
%J Australian Journal of Biological Sciences
%D 1970/04/01
%V 23
%N 2
%P 361-368
%K 
%R https://doi.org/10.1071/BI9700361
%U https://www.publish.csiro.au/paper/BI9700361 
%X The metabolism of carbaryl has been studied in the engorged adult female cattle tick, B. microplus using 14C·labelled compounds. Forty-eight hours after injection of [carbonyl-14C]carbaryl only 6% of the radioactivity could be recovered in an aqueous acetone extract while 90% was recoverable after an equivalent injection of [1-14C]carbaryl. Hydrolysis of the carbamate ester, hydroxylation, and conjugation were the major metabolic pathways. The radioactivity of the extract was completely accounted for as I-naphthol (55%) and 1,5-dihydroxynaphthalene (45%) after acid hydrolysis. 1,4-Dihydroxynaphthalene appears to be absent. Evidence was also obtained for some hydroxylation of the N-methyl group. No unchanged carbaryl could be detected. 
