
TY  - JOUR
A1  - Bend, JR 
A1  - Holder, GM 
A1  - Protos, Eva 
A1  - Ryan, AJ 
T1  - The Metabolism of Carbaryl in the Cattle Tick Boophilus Mioroplus (Canestrini)
JF  - Australian Journal of Biological Sciences
JO  - Aust. Jnl. Of Bio. Sci.
Y1  - 1970
VL  - 23
IS  - 2
SP  - 361
EP  - 368
KW  - 
UR  - https://doi.org/10.1071/BI9700361 
N2  - The metabolism of carbaryl has been studied in the engorged adult female cattle tick, B. microplus using 14C·labelled compounds. Forty-eight hours after injection of [carbonyl-14C]carbaryl only 6% of the radioactivity could be recovered in an aqueous acetone extract while 90% was recoverable after an equivalent injection of [1-14C]carbaryl. Hydrolysis of the carbamate ester, hydroxylation, and conjugation were the major metabolic pathways. The radioactivity of the extract was completely accounted for as I-naphthol (55%) and 1,5-dihydroxynaphthalene (45%) after acid hydrolysis. 1,4-Dihydroxynaphthalene appears to be absent. Evidence was also obtained for some hydroxylation of the N-methyl group. No unchanged carbaryl could be detected. 
ER  -

