
TY  - JOUR
A1  - McClure, TJ 
A1  - Nancarrow, CD 
A1  - Radford, HM 
T1  - The Effect of 2-Deoxy-N-Glucose on Ovarian Function of Cattle
JF  - Australian Journal of Biological Sciences
JO  - Aust. Jnl. Of Bio. Sci.
Y1  - 1978
VL  - 31
IS  - 2
SP  - 183
EP  - 186
KW  - 
UR  - https://doi.org/10.1071/BI9780183 
N2  - The administration of the metabolic inhibitor, 2-deoxY-D-glucose (2DG), to four well fed heifers just before and during the time of expected oestrus, and to another heifer following the removal of the corpus luteum, prevented both the occurrence of oestrus and the formation of corpora lutea in all animals. Plasma progesterone concentrations remained low for at least 10--21 days after the last dose of 2DG. The results suggest that the inhibition of glycolysis is associated with the failure of both oestrus and formation of functional corpora lutea, and· they support the hypothesis that hypoglycaemia is the primary biochemical change responsible for infertility induced by acute energy deficiency in lactating cattle. 
ER  -

