
%0 Journal Article
%A W Ward, Colin 
%A AA Dopheide, Theo 
%A S Inglis, Adam 
%T Amino Acid Sequence of Cyanogen Bromide Fragment CN2 From a Hong Kong Influenza Haemagglutinin Heavy Chain
%J Australian Journal of Biological Sciences
%D 1980/04/01
%V 33
%N 2
%P 137-152
%K 
%R https://doi.org/10.1071/BI9800137
%U https://www.publish.csiro.au/paper/BI9800137 
%X The amino acid sequence of cyanogen bromide peptide CN2 from the heavy chain (HAl) of the haemagglutinin of the Hong Kong variant A/Memphis/l02/72 has been obtained by direct, automated sequence analysis on the whole fragment and by manual dansyl-Edman degradation of tryptic, peptic and chymotryptic peptides. It was found to contain 92 amino acid residues, including a large, insoluble, tryptic core peptide (residues 62-87). It did not contain any half-cystine residues or carbohydrate. The determination of its structure was complicated by the presence of an Asn-Ile bond at positions 48-49 which was readily cleaved by both trypsin and chymotrypsin. 
