
TY  - JOUR
A1  - Faizi, Shaheen 
A1  - Siddiqui, Bina Shaheen 
A1  - Saleem, Rubeena 
A1  - Akhtar, Farzana 
A1  - Khan, Khursheed Ali 
A1  - Khan, Shakeel Ahmed 
A1  - Siddiqui, Salimuzzaman 
A1  - Parvez, Masood 
A1  - Choudhary, M. Iqbal 
T1  - Mannich Reaction Product of Quinolin-8-ol (Oxine) and its Antibacterial Activity
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1997
VL  - 50
IS  - 8
SP  - 861
EP  - 864
KW  - 
UR  - https://doi.org/10.1071/C96056 
N2  - Quinolin-8-ol (1) on reaction with 2,6-dichloroaniline and m-nitrobenzaldehyde afforded 7-(&#945;-hydroxy- m-nitrobenzyl)quinolin-8-ol (2), which is an unusual Mannich reaction product. The structure of (2) was determined by spectroscopic and single-crystal X-ray diffraction studies. Preliminary antimicrobial screening showed that (1) and (2) have activity against a large number of Gram-positive and Gram-negative bacteria. 
ER  -

