
%0 Journal Article
%A Bremner, John B. 
%A Rezaie, Robert 
%A Skelton, Brian W. 
%A White, Allan H. 
%T Synthesis of the Tetrahydrooxazolo[2,3-<emph type="2">b</emph>][3]benzazepin-3(2<emph type="2">H</emph>)-one System and X-Ray Crystal Structure of an 11a-Ethoxy Derivative
%J Australian Journal of Chemistry
%D 1997/09/05
%V 50
%N 7
%P 759-762
%K 
%R https://doi.org/10.1071/C97009
%U https://www.publish.csiro.au/paper/C97009 
%X Photolysis of the N-chloroacetyl imide derivative 3-chloroacetyl-7,8-dimethoxy-4,5-dihydro-1H-3-benzazepin-2(3H)-one (2) in aqueous acetonitrile gave 11a-hydroxy-8,9-dimethoxy-5,6,11,11a-tetrahydro-oxazolo&#91;2,3-b&#93;&#91;3&#93;benzazepin-3(2H)-one (4) in 81% yield. This representative of a new heterocyclic system could be converted into the 11a-ethoxy derivative (5) by recrystallization from ethanol. The structure of (5) was confirmed by a room-temperature single-crystal X-ray study. Crystals are monoclinic, Cc, a 17&#183;623(9), b 7&#183;550(4), c 12&#183;872(3) &#197;, &#946; 112&#183;55(4)&#176;, Z = 4; conventional R on F was 0&#183;034 for 1072 &#8216;observed&#8217; (I &#62; 3&#963;(I)) reflections. 
