
%0 Journal Article
%A Baradarani, Mehdi M. 
%A Clark, Adrian 
%A Prager, Rolf H. 
%T The Chemistry of 5-Oxodihydroisoxazoles. XXI Amidines and Pyrimidin-4-ones from the Reaction of Isoxazol-5(2<emph type="2">H</emph>)-ones with Amines
%J Australian Journal of Chemistry
%D 1998/06/03
%V 51
%N 6
%P 491-498
%K 
%R https://doi.org/10.1071/C97199
%U https://www.publish.csiro.au/paper/C97199 
%X While isoxazol-5(2H)-ones substituted with heterocycles at C2 but unsubstituted at C3 react with amines to give either amidines or malonamides, their reaction at low temperatures with lithium dialkylamides is a preparatively useful procedure for obtaining the amidines in most cases. Longer reaction times may lead to formation of pyrimidin-4-ones when ester groups are present at C4 of the isoxazolone. 
