
TY  - JOUR
A1  - Baradarani, Mehdi M. 
A1  - Clark, Adrian 
A1  - Prager, Rolf H. 
T1  - The Chemistry of 5-Oxodihydroisoxazoles. XXI Amidines and Pyrimidin-4-ones from the Reaction of Isoxazol-5(2<emph type="2">H</emph>)-ones with Amines
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1998
VL  - 51
IS  - 6
SP  - 491
EP  - 498
KW  - 
UR  - https://doi.org/10.1071/C97199 
N2  - While isoxazol-5(2H)-ones substituted with heterocycles at C2 but unsubstituted at C3 react with amines to give either amidines or malonamides, their reaction at low temperatures with lithium dialkylamides is a preparatively useful procedure for obtaining the amidines in most cases. Longer reaction times may lead to formation of pyrimidin-4-ones when ester groups are present at C4 of the isoxazolone. 
ER  -

