
TY  - JOUR
A1  - Dollt, Heribert 
A1  - Zabel, Volker 
T1  - Optically Pure Aminopolyols and Polyoxamic Acid Derivatives from Aziridine-2-carboxylates
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1999
VL  - 52
IS  - 4
SP  - 259
EP  - 270
KW  - 
UR  - https://doi.org/10.1071/C98026 
N2  - Various new chiral building blocks could easily be prepared from optically pure cis and trans ethyl 3-(1&#8242;,3&#8242;- dioxolan-4&#8242;-yl)aziridine-2-carboxylates. A stereochemically pure 1,3-dioxolan in the allyl position of an &#945;-bromoacrylate induced a high (3R*,4&#8242;S*) selectivity in the Michael addition with an amine. After oxygen at the inducing centre was exchanged with nitrogen bearing a bulky substituent, the directing influence of this new group was examined. Solvent effects influencing the cis/trans ratio of aziridine formation are discussed. 
ER  -

