
%0 Journal Article
%A Kendall, Jackie D. 
%A Woodgate, Paul D. 
%T Towards the Diastereoselective Functionalization of Non-Racemic Acetal Derivatives of &eta;<emph type="7">6</emph>-Arylcarbonyl Complexes of Tricarbonylchromium
%J Australian Journal of Chemistry
%D 1999/12/04
%V 51
%N 12
%P 1083-1096
%K 
%R https://doi.org/10.1071/C98054
%U https://www.publish.csiro.au/paper/C98054 
%X (S)-Butane-1,2,4-triol (2) has been investigated as a potential chiral auxiliary for the formation of non-racemic acetals derived from &#x03B7;6-arylcarbonyl complexes of tricarbonylchromium. Predominantly the cis dioxan (5) was formed from benzaldehyde, leading to preparation of the &#x03B7;6-Cr(CO)3 complex (16), and of the derived complexes (23) and (24). Lithiation&#123;electrophile quenching of these complexes gave a mixture of products arising fromortho and benzylic functionalization. Reaction of acetophenone, or of the &#x03B7;6-Cr(CO)3 complexes (45) or (46), with either the triol (2) or its tris(silyl) ether (15) under conditions of kinetic or thermodynamic control gave an inseparable mixture of acetals. 
