
TY  - JOUR
A1  - Katsifis, Andrew G. 
A1  - McPhee, Meredith E. 
A1  - Ridley, Damon D. 
T1  - Hydride Reductions of 1<emph type="2">H</emph>-Pyrrolo[2,1-c][1,4]-benzodiazepine-5,11-diones: Selective Reduction of Secondary Amides to Carbinolamines
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1999
VL  - 51
IS  - 12
SP  - 1121
EP  - 1130
KW  - 
UR  - https://doi.org/10.1071/C98079 
N2  - For the syntheses of radiolabelled pyrrolo&#91;1,4&#93;benzodiazepine antitumour antibiotics we required a method in which the unstable carbinolamine functionality was introduced prior to the radiolabel. In turn this required the selective reduction of a secondary amide in the presence of, inter alia, a tertiary amide. We report methods which can be used to achieve this outcome in a series of 1H-pyrrolo&#91;2,1-c&#93;&#91;1,4&#93;benzodiazepine-5,11-diones. 
ER  -

