
%0 Journal Article
%A Strauss, Christopher R. 
%A Trainor, Robert W. 
%T Reactions of Ethyl Indole-2-carboxylate in Aqueous Media at High Temperature
%J Australian Journal of Chemistry
%D 1998/08/18
%V 51
%N 8
%P 703-706
%K 
%R https://doi.org/10.1071/C98084
%U https://www.publish.csiro.au/paper/C98084 
%X Direct, preparative methods utilizing high-temperature aqueous media were developed for indole and indole-2-carboxylic acid from ethyl indole-2-carboxylate. Yields were excellent for these reactions, which were carried out in 1 h or less, at temperatures up to 270&#176;C, in a microwave batch reactor of the authors&quot; design. Avoidance of undesirable copper salts, high-boiling organic bases and heat-transfer oils made the methods environmentally benign. 
