
TY  - JOUR
A1  - Piggott, Matthew J. 
A1  - Wege, Dieter 
T1  - The Synthesis of Ventilone A
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 2000
VL  - 53
IS  - 9
SP  - 749
EP  - 754
KW  - Anthranilic acid; benzyne; oxazole; furan; cycloaddition.
UR  - https://doi.org/10.1071/CH00057 
N2  - 2-Amino-3,6-dimethoxy-4,5-methylenedioxybenzoic acid (12) was prepared from 1,4-dimethoxy-2,3-methylenedioxybenzene (8) via the isatin (11). The benzyne generated from (12) was intercepted with 3-acetyl-2-ethoxy-4-&#91;(4-methoxyphenoxy)methyl&#93;furan (4) to give the naphthol (27), which on treatment with cericammonium nitrate gave the dimethyl ether of ventilone A(29). Demethylation with boron tribromide then affordedventilone A (1). 
ER  -

