
%0 Journal Article
%A Zhu, Ying 
%A Zhu, Qi Xiu 
%A Jia, Zhong Jian 
%T Epoxide Sesquiterpenes and Steroids from <emph type="2">Cremanthodium discoideum</emph>
%J Australian Journal of Chemistry
%D 2001/04/05
%V 53
%N 10
%P 831-834
%K Sesquiterpene; steroid; antibacterial; cytoxicity; Compositae; Cremanthodium discoideum.
%R https://doi.org/10.1071/CH00100
%U https://www.publish.csiro.au/paper/CH00100 
%X Two new epoxide bisabolane sesquiterpenes and a new steroid were isolated from the whole plants of Cremanthodium discoideum Maxim. Their structures have been established by spectroscopic methods including two-dimensional n.m.r. (1H&#8211;1H COSY, 1H&#8211;1H NOESY, HMBC, HMQC) techniques. Six known steroids were also isolated and characterized. Compound (1) has antibacterial activity against Bacillus aeruginosus and B. subtilis. Two sesquiterpenes showed significant activity against two tumour cell lines: human promyelocytic leukemia cell HL-60 and human hapatoma cell SMMC-7721. 
