
%0 Journal Article
%A Smith, Graham 
%A White, Jonathan M. 
%T <emph type="2">Short Communication</emph>: Molecular Cocrystals of Carboxylic Acids: the Preparation of the 1: 1 Proton-Transfer Compounds of Creatinine with a Series of Aromatic Acids and the Crystal Structure of that with Pyrazine-2,3-dicarboxylic Acid
%J Australian Journal of Chemistry
%D 2001/08/01
%V 54
%N 2
%P 97-100
%K 
%R https://doi.org/10.1071/CH01009
%U https://www.publish.csiro.au/paper/CH01009 
%X The 1 : 1 proton-transfer compounds of creatinine with a series of aromatic carboxylic acids have been prepared and characterized using infrared spectroscopy and in one case with single-crystal X-ray crystallography. The acids are the mononitro-substituted benzoic acids 3,5-dinitrobenzoic acid, 5-nitrosalicylic acid, 3,5-dinitrosalicylic acid and pyrazine-2,3-dicarboxylic acid. The crystal structure of the compound with pyrazine-2,3-dicarboxylic acid, &#91;(C4H8N3O+)(C6H3N2O4&#8211;)&#93;, shows a chain structure based on a primary asymmetric cyclic hydrogen-bonding dimer formed through the carboxylate group and the hetero-nitrogen of the acid, and the protonated imine and the adjacent hetero-amine proton of creatinine. Peripheral extension is through the second imine proton to the second carboxylic acid group of an adjacent acid molecule. Manuscript received: 1 February 2001. 
